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Medicines paliperidoneQuestion & answer

paliperidone · Medicine question

Which serotonin and dopamine receptors does paliperidone block?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Paliperidone blocks serotonergic 5-HT2 receptors and dopaminergic D2 receptors, binding strongly to both.

Sources for this answer

Invega 3 mg prolonged-release tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated 3 July 2025

Sources checked 8 November 2026

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paliperidone

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