Answer
Paliperidone may antagonise levodopa’s effect; if the combination is necessary, particularly in end-stage Parkinson’s disease, the lowest effective dose of each treatment should be prescribed.
Sources for this answer
- Invega 3 mg prolonged-release tabletsJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated
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