irinotecan sucrosofate · Medicine question

Which enzymes convert irinotecan released from Onivyde pegylated liposomal into its active metabolite SN-38?

Name: Which enzymes convert irinotecan released from Onivyde pegylated liposomal into its active metabolite SN-38?
Published: 2026-11-08T14:21:38.905Z

iatroX medicinesPublished 8 November 2026

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Carboxylesterase enzymes convert irinotecan released from Onivyde pegylated liposomal into its active metabolite SN-38.

Sources for this answer

ONIVYDE pegylated liposomal 4.3 mg/ml concentrate for dispersion for infusionServier Laboratories Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 13Document updated 27 May 2025

Sources checked 8 November 2026

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