colchicine · Medicine question

What serious bone marrow effects can colchicine cause?

iatroX medicinesPublished 8 November 2026

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Colchicine can cause severe bone marrow depression, including agranulocytosis, aplastic anaemia and thrombocytopenia, with blood-count changes developing gradually or suddenly and aplastic anaemia carrying a high mortality rate.

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Colchicine 500 micrograms TabletsWockhardt UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 9Document updated 31 July 2025

Sources checked 8 November 2026

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