colchicine · Medicine question

How is colchicine thought to reduce inflammation in gout?

iatroX medicinesPublished 8 November 2026

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Colchicine’s mechanism in gout is not clearly understood, but it may reduce the inflammatory response to urate crystals by inhibiting granulocyte migration into inflamed areas, with microtubule interactions possibly contributing.

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Colchicine 500 micrograms TabletsWockhardt UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 9Document updated 31 July 2025

Sources checked 8 November 2026

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