Answer
Combining posaconazole and midazolam risks prolonged sedation and possible respiratory depression, so co-administration should only be considered if clearly necessary, with consideration of midazolam dose adjustment.
Sources for this answer
- Noxafil 40mg/ml oral suspensionMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 29Document updated
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