Answer
Esomeprazole reduces absorption of posaconazole oral suspension: esomeprazole 40 mg daily with posaconazole 400 mg decreased mean peak plasma concentration by 46% and overall exposure by 32% versus posaconazole alone, so co-administration should be avoided if possible.
Sources for this answer
- Noxafil 40mg/ml oral suspensionMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 29Document updated
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