sacubitril + valsartan · Medicine question

What kidney-related risk is associated with taking NSAIDs alongside sacubitril + valsartan in elderly patients?

Name: What kidney-related risk is associated with taking NSAIDs alongside sacubitril + valsartan in elderly patients?
Published: 2026-11-08T02:02:22.993Z

iatroX medicinesPublished 8 November 2026

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In elderly patients, taking NSAIDs alongside sacubitril + valsartan may increase the risk of worsening kidney function, so renal function monitoring is recommended when treatment is initiated or modified.

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Entresto film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 14Document updated 30 September 2025

Sources checked 8 November 2026

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