orlistat · Medicine question

What is the main route of elimination of orlistat?

iatroX medicinesPublished 8 November 2026

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Orlistat is eliminated mainly through faecal excretion of unabsorbed drug, with approximately 97% of the administered dose excreted in faeces and 83% of that as unchanged orlistat.

Sources for this answer

Xenical 120 mg hard capsulesNeon Healthcare Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 3Document updated 24 October 2023

Sources checked 8 November 2026

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