orlistat · Medicine question

Has serious hepatitis been reported with orlistat?

iatroX medicinesPublished 8 November 2026

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Answer

Yes, potentially serious hepatitis has been reported with orlistat, including fatal cases and cases requiring liver transplantation, with frequency unknown.

Sources for this answer

alli 60 mg hard capsulesHaleon UK Trading Limited · emc · SmPC §4.8 Undesirable effects · Version 12Document updated 25 April 2023

Sources checked 8 November 2026

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