sacubitril + valsartan · Medicine question

What is known about the effects of sacubitril + valsartan on human fertility?

Name: What is known about the effects of sacubitril + valsartan on human fertility?
Published: 2026-11-08T14:29:29.509Z

iatroX medicinesPublished 8 November 2026

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There are no available data on the effects of sacubitril + valsartan on human fertility, although studies in male and female rats demonstrated no impairment of fertility.

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Entresto film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 15Document updated 29 April 2026

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