What is immune reactivation syndrome in people with HIV and severe immune deficiency starting combination antiretroviral therapy containing abacavir + lamivudine?

Immune reactivation syndrome in people with HIV and severe immune deficiency starting combination therapy containing abacavir + lamivudine is an inflammatory reaction to asymptomatic or residual opportunistic infections; autoimmune disorders can also occur during immune reconstitution, sometimes many months after treatment starts.