Answer
In two dedicated QT studies, supratherapeutic pitolisant hydrochloride doses of 108–216 mg (3–6 times the therapeutic dose) produced mild to moderate QTc prolongation of 10–13 ms.
Sources for this answer
- Wakix 4.5 mg film-coated tabletsBioprojet UK Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 6Document updated
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