What conditions is pamidronate disodium used to treat or prevent?

Pamidronate disodium treats tumour-induced hypercalcaemia and Paget’s disease of bone and, alongside tumour-specific treatment, prevents skeletal-related events (pathological fractures, spinal compression, radiation or surgery to bone, hypercalcaemia and bone pain) in patients with breast cancer with bone metastases or multiple myeloma with bone lesions.