Answer
Macitentan and its active metabolite aprocitentan have apparent elimination half-lives of approximately 16 hours and 48 hours, respectively.
Sources for this answer
- Opsumit 10mg film coated tablets (Great Britain)Janssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.2 Pharmacokinetic properties · Version 29Document updated
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