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Medicines calcium folinateQuestion & answer

calcium folinate · Medicine question

What allergic reactions have been reported with calcium folinate?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Anaphylactoid reactions and urticaria have been reported with calcium folinate (leucovorin).

Sources for this answer

Refolinon TabletsPfizer Limited · emc · SmPC §4.8 Undesirable effects · Version 8Document updated 22 November 2016

Sources checked 8 November 2026

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calcium folinate

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What are the most common dose-limiting adverse effects of calcium folinate combined with 5-fluorouracil?By what route are Refolinon calcium folinate tablets administered?Can calcium folinate be administered intrathecally?Can calcium folinate be used with 5-fluorouracil during breastfeeding?Have adequate, well-controlled studies of calcium folinate been conducted in pregnant women?How does calcium folinate affect the toxicity of fluorouracil?

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