Can calcium folinate be used with 5-fluorouracil during breastfeeding?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Calcium folinate combined with 5-fluorouracil is contraindicated during breastfeeding.

Refolinon TabletsPfizer Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 8Document updated 22 November 2016

Sources checked 8 November 2026

loading page…

learn & practise

clinical reference

trust & support

legal

calcium folinate · Medicine question

iatroX medicinesPublished 8 November 2026

The answer

Calcium folinate combined with 5-fluorouracil is contraindicated during breastfeeding.

Refolinon TabletsPfizer Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 8Document updated 22 November 2016

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

The full medicine guide

Read the wider context, including uses, precautions and the sources behind this medicine guide.