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Medicines calcium folinateQuestion & answer

calcium folinate · Medicine question

How does calcium folinate affect the toxicity of fluorouracil?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Calcium folinate may enhance the toxicity of fluorouracil.

Sources for this answer

Refolinon TabletsPfizer Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated 22 November 2016

Sources checked 8 November 2026

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The full medicine guide

calcium folinate

Read the wider context, including uses, precautions and the sources behind this medicine guide.

More questions about calcium folinate

Can calcium folinate be used with 5-fluorouracil during breastfeeding?What are the most common dose-limiting adverse effects of calcium folinate combined with 5-fluorouracil?By what route are Refolinon calcium folinate tablets administered?Can calcium folinate be administered intrathecally?Have adequate, well-controlled studies of calcium folinate been conducted in pregnant women?Is it known whether calcium folinate passes into human breast milk?

Read the calcium folinate guide

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