Dr Kola Tytler MBBS CertHE MBA MSt MRCGPClinical Lead • iatroX
CBT-I is the preferred first-line treatment for adults with chronic insomnia because its benefits persist after treatment ends, whereas pharmacological therapy should be avoided for long-term management. NICE CKS
- Durable benefit: CBT-I produces benefits that persist after completion, unlike medication. NICE CKS
- Appropriate across adulthood: CBT-I is recommended for chronic insomnia in adults of any age, including via the NICE-recommended digital CBT-I programme Sleepio. NICE CKS
- Avoids long-term hypnotic exposure: NICE advises avoiding pharmacological therapy in long-term insomnia management, and hypnotics should be avoided where possible because of their potential for significant adverse effects. NICE CKS
- Addresses maintaining mechanisms: CBT-I is particularly relevant because maladaptive behaviours and cognitions are thought to contribute to chronic insomnia. NICE CKS
- Medication has a limited role: A short course of a non-benzodiazepine hypnotic may be considered only as adjunctive treatment in selected circumstances, rather than as the core long-term treatment for chronic insomnia. NICE CKS
- Consistent with product information: Zopiclone is indicated for short-term treatment, with long-term continuous use not recommended and the lowest effective dose advised. SmPC Zopiclone,SmPC Zopiclone
For primary-care practice, prioritise referral or access to CBT-I, including digital CBT-I where suitable, alongside assessment of comorbid physical or mental health conditions and other sleep disorders that may require targeted management. NICE CKS
Key References
- NICE CKS: Insomnia
- SmPC: QUVIVIQ 25 mg film-coated tablets
- SmPC: QUVIVIQ 50 mg film-coated tablets
- SmPC: Zopiclone 3.75mg film-coated tablets
- SmPC: Zopiclone 7.5mg film-coated tablets
- NICE CKS: Restless legs syndrome
- NICE CG78: Borderline personality disorder: recognition and management
- NICE CG170: Autism spectrum disorder in under 19s: support and management
- NICE NG202: Obstructive sleep apnoea/hypopnoea syndrome and obesity hypoventilation syndrome in over 16s
- NICE NG116: Post-traumatic stress disorder