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Which laboratory tests are recommended for the diagnosis of spondyloarthritis in primary care?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

In primary care, the recommended laboratory test for suspected spondyloarthritis is an HLA‑B27 test, which should be performed if the clinical suspicion remains after initial assessment or if the MRI does not meet the ASAS/OMERACT MRI criteria for non-radiographic axial spondyloarthritis 1.

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