Liver Function Tests (LFTs)

Interpretation of liver enzymes and function markers.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP (General Practitioner)

Last reviewed: 21 October 2025

HepatologyGastroenterologyBiochemistry

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regional clinical guidance

Liver Function Tests (LFTs): guidance by region

Recommendations, thresholds and pathways can differ. Open the page written for the jurisdiction you need.

United StatesEvaluation of abnormal liver chemistriesDigestive · reviewed 2026-08-20 CanadaAbnormal liver blood tests (LFTs): structured primary care approachDigestive · reviewed 2026-08-20 AustraliaAbnormal liver blood tests (LFTs): structured primary care approachDigestive · reviewed 2026-08-20

Clinical Guidelines

Abnormal liver function tests (LFTs) in asymptomatic patient in primary care

Guidelines on the management of abnormal liver blood tests

Management of Abnormal LFTs in Asymptomatic Adults - North & East

2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute cholangitis (Tokyo Guidelines 2018)

ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries

ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury

AHA/ACC/HFSA Guideline for the Management of Heart Failure

British Association of Urological Surgeons Consensus statements on the management of ketamine-induced uropathy

International Liver Transplantation Society Consensus Statement on Antibody-Mediated Rejection in Liver Transplantation