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Cancer-associated pulmonary embolism — SCE Respiratory MCQ

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ModeratePulmonary Vascular DiseaseCancer-associated pulmonary embolismSCE Respiratory

A 57-year-old woman with metastatic pancreatic cancer has incidental segmental PE on staging CT. She is asymptomatic, platelet count is 170 x 10^9/L and creatinine clearance is 75 mL/min. What is the most appropriate management?

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Correct answer: DOffer therapeutic anticoagulation unless bleeding risk outweighs benefit

Incidental segmental PE in active cancer is usually treated with therapeutic anticoagulation after bleeding risk assessment. Lack of symptoms does not make segmental PE benign in this context. Aspirin, thrombolysis and first-line IVC filter are inappropriate without specific indications.

Reference: NICE NG158; BNF