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Nodal staging of NSCLC — SCE Respiratory MCQ

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ModerateLung CancerNodal staging of NSCLCSCE Respiratory

A 62-year-old woman with a peripheral lung adenocarcinoma has PET-negative mediastinum but enlarged N1 hilar nodes on CT. Surgical resection is being considered. What is the most appropriate investigation?

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Correct answer: D — EBUS-guided sampling of suspicious hilar or mediastinal nodes if accessible

Enlarged or suspicious nodes should be sampled where accessible because PET can miss nodal disease and nodal stage changes management. Serum tumour markers do not replace tissue staging. Palliative radiotherapy and airway challenge are not appropriate next steps in potentially resectable lung cancer.

Reference: NICE NG122