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Rheumatoid arthritis-associated ILD — SCE Respiratory MCQ

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HardILDRheumatoid arthritis-associated ILDSCE Respiratory

A 62-year-old man with rheumatoid arthritis develops progressive dyspnoea. HRCT shows a UIP pattern and FVC has fallen from 82% to 67% predicted over 12 months despite optimised joint control. He is not a current smoker and infection has been excluded. What is the most appropriate management?

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Correct answer: EDiscuss antifibrotic therapy for progressive fibrosing ILD in an ILD MDT

A substantial FVC decline with progressive fibrosis in rheumatoid arthritis-associated UIP indicates a progressive pulmonary-fibrosis phenotype. The ILD multidisciplinary team should reassess inflammatory treatment and consider antifibrotic therapy under NICE guidance. Long-term high-dose corticosteroid is not the default for established fibrotic UIP.

Reference: https://www.nice.org.uk/guidance/ta747