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Limited-stage small-cell lung cancer — SCE Respiratory MCQ

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ModerateLung CancerLimited-stage small-cell lung cancerSCE Respiratory

A 66-year-old woman has limited-stage small-cell lung cancer confined to one hemithorax and mediastinum. ECOG performance status is 1 and renal function is normal. Brain MRI is negative. What is the most appropriate management?

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Correct answer: D — Platinum-etoposide chemotherapy with concurrent thoracic radiotherapy

Fit patients with limited-stage SCLC are usually treated with platinum-etoposide chemotherapy and thoracic radiotherapy with curative intent. Surgery alone is not standard for most limited-stage SCLC. Pleurodesis treats recurrent malignant effusion but does not control limited-stage small-cell cancer.

Reference: NICE NG122 Lung Cancer; ESMO SCLC Guideline