skip to main content

Cystic fibrosis Pseudomonas acquisition — SCE Respiratory MCQ

Instant feedback + full explanation. One question, done properly.

ModerateRespiratory InfectionsCystic fibrosis Pseudomonas acquisitionSCE Respiratory

A 19-year-old woman with cystic fibrosis has increased cough and a first sputum isolate of Pseudomonas aeruginosa. FEV1 is 82% predicted and she is clinically stable after oral antibiotics. What is the most appropriate management?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Attempt early Pseudomonas eradication therapy

First isolation of Pseudomonas in cystic fibrosis should prompt eradication therapy to reduce the chance of chronic infection. Waiting for chronic colonisation worsens long-term airway infection risk. Preserved FEV1 does not remove the need to address first Pseudomonas acquisition.

Reference: Cystic Fibrosis Trust Standards of Care; NICE NG78