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Limited-stage small-cell lung cancer — SCE Respiratory MCQ

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HardLung CancerLimited-stage small-cell lung cancerSCE Respiratory

A 66-year-old man has limited-stage small-cell lung cancer with good performance status. Staging CT and brain MRI show disease confined to one hemithorax and ipsilateral mediastinal nodes. What is the most appropriate management?

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Correct answer: CConcurrent platinum-etoposide chemotherapy and thoracic radiotherapy

Limited-stage SCLC in a fit patient is treated with platinum-etoposide chemotherapy plus thoracic radiotherapy. Surgery alone is not standard for node-positive SCLC. EGFR inhibitors are used for EGFR-mutant NSCLC, not SCLC.

Reference: NICE NG122; ESMO SCLC Guideline