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Liver Metastasectomy 5yr — SCE Medical Oncology MCQ

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EasyGI CancersLiver Metastasectomy 5yrSCE Medical Oncology

A 60-year-old man with metastatic CRC has a liver-only oligometastatic presentation (3 lesions, all resectable). His primary tumour has been resected. He asks about the 5-year survival after liver metastasectomy. What is the expected outcome?

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Correct answer: B — Approximately 40-50% 5-year survival after R0 hepatic metastasectomy for CRC

CRC liver metastasectomy: 5-year OS ~40-50% after R0 resection (Fong score, Adam et al). Strongest predictors: completeness of resection (R0), number of lesions, CEA level, node-positive primary, and disease-free interval. Perioperative chemotherapy (EPOC trial: FOLFOX 3 months pre + 3 months post) is commonly used though the EPOC OS data is debated.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cancer