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IDEA Adjuvant Duration — SCE Medical Oncology MCQ

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EasyGI CancersIDEA Adjuvant DurationSCE Medical Oncology

A 60-year-old man with CRC develops liver metastases. His oncologist discusses the IDEA collaborative analysis of adjuvant chemotherapy duration. What was the key finding of IDEA?

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Correct answer: A — For LOW-RISK stage III CRC (T1-3

IDEA (6 trials, 12,800 patients): 3 vs 6 months adjuvant chemo for stage III CRC. Low-risk T1-3N1: 3 months CAPOX non-inferior. High-risk T4/N2: 6 months still recommended. 3 months CAPOX reduces grade 2+ neuropathy from ~48% to ~15%.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cancer