skip to main content

Anti-EGFR Skin Care — SCE Medical Oncology MCQ

Instant feedback + full explanation. One question, done properly.

EasyGI CancersAnti-EGFR Skin CareSCE Medical Oncology

A 55-year-old woman with CRC on cetuximab is advised about sun protection. What skin-specific counselling is important during anti-EGFR therapy?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Broad-spectrum SPF 50+ sunscreen is essential

Patients on anti-EGFR therapy (cetuximab, panitumumab) require comprehensive skin care counselling: (1) broad-spectrum SPF 50+ sunscreen (UV exposure exacerbates the rash), (2) emollients (fragrance-free, applied twice daily), (3) avoid harsh soaps/hot water, (4) gentle cleansing, (5) prophylactic doxycycline 100 mg daily from day 1 (reduces rash severity by ~50%, STEPP trial). This proactive approach significantly reduces grade 2+ skin toxicity and maintains quality of life and drug dose intensity.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cancer