A 62-year-old man with locally advanced laryngeal SCC (T3 N0 M0, glottic) is offered either total laryngectomy or larynx-preserving concurrent

Question

A 62-year-old man with locally advanced laryngeal SCC (T3 N0 M0, glottic) is offered either total laryngectomy or larynx-preserving concurrent chemoradiotherapy. The VA Laryngeal Cancer Study and RTOG 91-11 trials established what principle?

Accepted Answer

Concurrent chemoradiotherapy can preserve the larynx (and voice) in approximately 60-70% of patients with locally advanced laryngeal cancer without compromising overall survival

Answer

Laryngectomy is always superior as the preferred next management strategy at this stage in the clinical context described

Answer

Radiotherapy alone is sufficient for all laryngeal cancers as the preferred next management strategy at this stage in the clinical context described

Answer

Chemotherapy alone cures laryngeal cancer as the preferred next management strategy at this stage in the clinical context described

Answer

Only laser surgery preserves the larynx as the preferred next management strategy at this stage in the clinical context described

Larynx Preservation — SCE Medical Oncology MCQ

A 62-year-old man with locally advanced laryngeal SCC (T3 N0 M0, glottic) is offered either total laryngectomy or larynx-preserving concurrent chemoradiotherapy. The VA Laryngeal Cancer Study and RTOG 91-11 trials established what principle?