Breast Cancer in Pregnancy — SCE Medical Oncology MCQ
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Correct answer: D — Anthracycline-based chemotherapy without trastuzumab
Anthracyclines are safe in 2nd/3rd trimester. Trastuzumab is CONTRAINDICATED in pregnancy (causes oligo/anhydramnios). Anti-HER2 agents deferred until after delivery.
Reference: ESMO 2024 Breast Cancer in Pregnancy Guidelines; Amant et al Lancet 2012