skip to main content

Breast Cancer — SCE Medical Oncology MCQ

Instant feedback + full explanation. One question, done properly.

ModerateBreast CancerBreast CancerSCE Medical Oncology

A 45-year-old woman has high genomic risk on MammaPrint despite favourable clinical features. What does the MINDACT trial suggest?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BHigh genomic risk identifies patients who benefit from chemotherapy even when clinical risk appears low

MINDACT showed clinical low-risk/genomic high-risk patients benefit from adjuvant chemotherapy (~8% DMFS improvement). This identifies undertreated patients based on clinicopathology alone.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cancer