Breast Cancer — SCE Medical Oncology MCQ
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Correct answer: B — High genomic risk identifies patients who benefit from chemotherapy even when clinical risk appears low
MINDACT showed clinical low-risk/genomic high-risk patients benefit from adjuvant chemotherapy (~8% DMFS improvement). This identifies undertreated patients based on clinicopathology alone.
Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cancer