CIPN — SCE Medical Oncology MCQ

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ModerateSupportive & Palliative OncologyCIPNSCE Medical Oncology

A patient has painful chemotherapy-induced peripheral neuropathy persisting after paclitaxel. Which medicine has the best evidence for symptomatic treatment?

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Correct answer: C — Duloxetine

Duloxetine has the strongest evidence for painful established chemotherapy-induced peripheral neuropathy. Benefit is incomplete, so also assess functional impairment, falls risk and reversible contributors and use rehabilitation and safety measures. Dose modification or cessation of the causative chemotherapy is a separate preventive decision during active treatment.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cancer