Malignant Bowel Obstruction — SCE Medical Oncology MCQ
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Correct answer: B — Replace or escalate the antisecretory strategy to octreotide
NICE advises hyoscine butylbromide first and octreotide when obstructive vomiting has not improved within 24 hours. Laxatives and loperamide can worsen complete obstruction, parenteral nutrition is not an acute antiemetic, and surgery depends on anatomy and fitness rather than vomiting alone.
Reference: NICE NG31: care of dying adults. https://www.nice.org.uk/guidance/ng31/chapter/Recommendations