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Endometrial Cancer — SCE Medical Oncology MCQ

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HardGynaecological CancersEndometrial CancerSCE Medical Oncology

After hysterectomy, pathology shows grade 1 endometrioid endometrial carcinoma with cervical stromal invasion, less than 50% myometrial invasion and no substantial LVSI. Molecular testing shows NSMP. Under FIGO 2023, which anatomical stage descriptor is correct?

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Correct answer: C — Stage IIA because non-aggressive histology involves the cervical stroma

FIGO 2023 assigns non-aggressive histology with cervical stromal invasion to stage IIA. Stage IIB is substantial LVSI, not cervical invasion. IA2 is low-grade disease with less than 50% myometrial invasion only when the stage-II feature is absent; IB and IIIC1 do not fit.

Reference: FIGO staging of endometrial cancer 2023. https://pmc.ncbi.nlm.nih.gov/articles/PMC10482588/