A patient with metastatic breast cancer has a completed pathological fracture through a lytic proximal femoral metastasis. She was independently

Question

A patient with metastatic breast cancer has a completed pathological fracture through a lytic proximal femoral metastasis. She was independently mobile before the fracture and has an expected survival measured in years. Which integrated plan addresses mechanical and oncological risk?

Accepted Answer

Orthopaedic stabilisation, postoperative radiotherapy and initiation of a bone-modifying agent

Answer

Radiotherapy followed by unrestricted weight bearing across the unstable fracture

Answer

Bed rest and analgesia until systemic therapy produces radiological recalcification

Answer

External fixation as definitive treatment followed by endocrine therapy alone

Answer

Denosumab followed by delayed fixation if the fracture remains displaced

Bone Metastases — SCE Medical Oncology MCQ

A patient with metastatic breast cancer has a completed pathological fracture through a lytic proximal femoral metastasis. She was independently mobile before the fracture and has an expected survival measured in years. Which integrated plan addresses mechanical and oncological risk?