A 45-year-old woman on ICU has acute pancreatitis. CT at 72 hours shows >30% pancreatic necrosis. She is haemodynamically stable and clinically improving on antibiotics. Should prophylactic antibiotics be continued for sterile pancreatic necrosis?AYes - prophylactic antibiotics should be given for all pancreatic necrosis to prevent infectionBNo - current evidence (including meta-analyses and guidelines) does not support routine prophylactic antibiotics for sterile pancreatic necrosis; antibiotics should only be used when infection is confirmed or strongly suspectedCYes - all patients with pancreatitis require antibioticsDOnly antifungal prophylaxis is neededEProbiotics should replace antibioticsCheck my answer