A 65-year-old man on ICU has been on propofol sedation for 10 days. The team considers switching to dexmedetomidine for its wake-sedation properties. When transitioning from propofol to dexmedetomidine, what loading dose approach is recommended?AAlways give a dexmedetomidine loading dose of 1 mcg/kg over 10 minutesBIn ICU patients, omit or reduce the loading dose due to the risk of bradycardia and hypotension - start a maintenance infusion (0.2-1.4 mcg/kg/hr) and titrate, overlapping with propofol taperCStop propofol abruptly and start dexmedetomidine at maximum doseDLoading doses are mandatory for all patientsENo dose adjustment is ever neededCheck my answer