A 62-year-old man on ICU is receiving therapeutic anticoagulation with rivaroxaban (a direct oral anticoagulant - DOAC) for atrial fibrillation. He de...

Question

A 62-year-old man on ICU is receiving therapeutic anticoagulation with rivaroxaban (a direct oral anticoagulant - DOAC) for atrial fibrillation. He develops a life-threatening GI haemorrhage. What is the specific reversal agent for rivaroxaban?

Accepted Answer

Andexanet alfa - a recombinant modified Factor Xa decoy protein that binds and reverses Factor Xa inhibitors

Answer

Protamine sulphate

Answer

Vitamin K

Answer

Idarucizumab

Answer

Fresh frozen plasma

uk-fficm MCQ (SBA): DOAC Reversal

A 62-year-old man on ICU is receiving therapeutic anticoagulation with rivaroxaban (a direct oral anticoagulant - DOAC) for atrial fibrillation. He develops a life-threatening GI haemorrhage. What is the specific reversal agent for rivaroxaban?