testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate at a glance
Medicine class
Androgen and testosterone replacement therapy
Administration
Given slowly by deep injection into a muscle by a doctor or nurse
Important allergy
Contains refined peanut oil; it must not be used with peanut or soya allergy
Fertility
Can suppress sperm production and does not provide contraception
What is testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate used for?
Licensed uses represented by the selected product are:
Testosterone replacement for male hypogonadism confirmed by symptoms and biochemical testing.
Supportive masculinising hormone therapy for trans men under specialist care.
How does testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate work?
The four esters are converted in the bloodstream into testosterone. Their differing release profiles provide sustained androgen exposure. Testosterone acts through androgen receptors and is also metabolised to dihydrotestosterone and estradiol.
How to take testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate
A doctor or nurse gives the oily solution slowly by deep intramuscular injection. The patient should be observed during and immediately after administration for breathing or circulatory symptoms.
Do not self-inject unless a suitably qualified clinical team has trained and authorised you.
Before injection, tell the clinician about peanut or soya allergy, new medicines, pregnancy risk or significant new symptoms.
testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate side effects
Common or expected effects
- Increased red blood cell count, haemoglobin or haematocrit
- Weight gain
- Injection-site reactions
Get urgent medical advice
- Symptoms of a blood clot, including one-sided leg swelling, sudden breathlessness, chest pain or sudden visual loss
- Sudden cough, breathlessness, sweating, chest pain, dizziness or fainting during or immediately after injection
- Prolonged painful erection
- Marked fluid retention, breathlessness or worsening heart failure
- Severe allergic reaction
testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate in pregnancy
This product is contraindicated during pregnancy because fetal virilisation is possible. Testosterone is not contraception, and pregnancy can still occur. Contact the prescriber immediately if pregnancy is suspected and obtain specialist advice before trying to conceive.
testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate while breastfeeding
This product is contraindicated during breastfeeding because adequate product-specific safety data are unavailable. Discuss alternatives and timing with the specialist team if planning to breastfeed or chestfeed.
testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate interactions
Tell the prescriber about all prescribed, over-the-counter and complementary treatments. Important interactions include:
Insulin and other glucose-lowering medicines
Testosterone may improve glucose tolerance, so glucose monitoring and adjustment of diabetes treatment may be needed.
SGLT-2 inhibitors
Combined use may further increase haematocrit, requiring closer haemoglobin and haematocrit monitoring.
Coumarin anticoagulants
Androgens may strengthen anticoagulant effects, so clotting tests may need closer monitoring.
Common questions about testosterone decanoate + testosterone isocaproate + testosterone phenylpropionate + testosterone propionate
Answers are fully visible for fast scanning and source review.
Does it contain peanut oil?
Yes. It contains refined arachis oil and must not be used by people allergic to peanuts or soya.
Can it increase red blood cells?
Yes. It can raise haemoglobin and haematocrit and may cause polycythaemia, so regular blood counts are important.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.