sodium acid phosphate at a glance
Medicine class
Oral inorganic phosphate
Licensed uses
Selected hypercalcaemia and hypophosphataemic vitamin D-resistant bone disorders
Form
Effervescent tablet that must be completely dissolved in water before drinking
Important ingredients
Contains substantial sodium, as well as potassium and sucrose
What is sodium acid phosphate used for?
Licensed uses of the selected product include:
Hypercalcaemia associated with hyperparathyroidism, multiple myeloma or other malignancy.
Hypophosphataemia associated with vitamin D-resistant rickets or vitamin D-resistant hypophosphataemic osteomalacia.
How does sodium acid phosphate work?
Oral phosphate replaces phosphate absorbed through the intestine. In hypercalcaemia, it can also bind calcium in the gut, reducing calcium absorption and lowering blood calcium.
How to take sodium acid phosphate
Use exactly as directed by the prescriber. This is an effervescent preparation and should not be swallowed whole.
Dissolve the tablet completely in roughly one-third to one-half of a glass of water.
Drink the solution after it has finished dissolving.
Keep the tube tightly closed and protect the tablets from moisture.
sodium acid phosphate side effects
Common or expected effects
- Gastrointestinal upset
- Nausea
- Diarrhoea
Get urgent medical advice
- Difficulty breathing or swelling of the face, lips, tongue or throat may indicate a severe allergic reaction.
- Excessive exposure can cause hypocalcaemia and requires prompt clinical assessment.
sodium acid phosphate in pregnancy
Formal pregnancy safety studies are lacking, although the product information reports longstanding use without identified ill effects. Treatment should still be reviewed by the prescriber, particularly where kidney impairment, hypertension, pre-eclampsia or sodium restriction is relevant.
sodium acid phosphate while breastfeeding
The product information does not provide specific breastfeeding safety data. A prescriber or pharmacist should assess the need for treatment and the circumstances of the parent and infant; specialist advice is particularly useful for premature or medically unwell infants.
sodium acid phosphate interactions
Tell the prescriber or pharmacist about prescribed, over-the-counter and complementary products.
Aluminium-containing antacids
They may interfere with calcium binding by oral phosphate and reduce its intended effect.
Common questions about sodium acid phosphate
Answers are fully visible for fast scanning and source review.
Is sodium acid phosphate a phosphate supplement or a phosphate binder?
It is principally an oral phosphate supplement. In hypercalcaemia, its phosphate can also bind calcium in the gut and reduce calcium absorption.
Why does sodium acid phosphate require blood-test monitoring?
Monitoring checks the phosphate and calcium response and helps detect electrolyte imbalance or excessive treatment.
Can sodium acid phosphate be taken with an antacid?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.