latanoprost + timolol maleate at a glance
Medicine class
Fixed combination of a prostaglandin analogue and a non-selective beta blocker.
Licensed use
Raised eye pressure in adults when a topical beta blocker or prostaglandin analogue alone is insufficient.
Reduce absorption
Close the eye and press gently at its inner corner for two minutes after application.
Contact lenses
Remove lenses before application and wait 15 minutes before replacing them.
What is latanoprost + timolol maleate used for?
Licensed in adults, including older adults, to reduce pressure inside the eye.
Open-angle glaucoma when a topical beta blocker or prostaglandin analogue alone is insufficient.
Ocular hypertension when either treatment type alone is insufficient.
Safety and effectiveness in children and adolescents have not been established for the selected products.
How does latanoprost + timolol maleate work?
Latanoprost increases fluid drainage from the eye. Timolol reduces fluid production. Together, these actions lower eye pressure.
latanoprost + timolol maleate preparations and strengths
Eye drops
Route: Ophthalmic
Strengths: 50 micrograms/mL + 5 mg/mL
How to take latanoprost + timolol maleate
Use exactly as prescribed and follow the instructions for your specific container.
Wash your hands and do not touch the bottle tip to the eye, eyelid or another surface.
After application, close the eye and press gently beside the nose for two minutes.
Leave at least five minutes between different eye medicines.
Remove contact lenses first and wait 15 minutes before replacing them.
Vizilatan Duo's pump requires priming before first use; a temporary whitish appearance during priming is not harmful.
Do not drive or operate machinery until temporary blurred vision clears.
latanoprost + timolol maleate side effects
Common or expected effects
- Gradual increase in brown iris pigmentation, which may be permanent
- Eye pain, stinging, burning, itching or a gritty sensation
- Redness, watering or temporary blurred vision
- Inflamed eyelids or conjunctivitis
- Longer, thicker, darker or misdirected eyelashes
Get urgent medical advice
- Wheezing, bronchospasm or difficulty breathing
- Markedly slow or irregular heartbeat, fainting or chest pain
- Severe allergic reaction, including facial or throat swelling
- New eye pain with reduced vision
latanoprost + timolol maleate in pregnancy
The selected combination-product information states that it should not be used during pregnancy. Anyone pregnant or planning pregnancy should obtain specialist medication advice rather than stopping treatment independently.
latanoprost + timolol maleate interactions
Timolol can enter the bloodstream. Review other eye treatments and medicines affecting heart rate, blood pressure or glucose control.
Oral or ophthalmic beta blockers
May increase beta blockade, excessively slowing the heart or lowering blood pressure. Two topical beta blockers are not recommended.
Calcium-channel blockers, antiarrhythmics or digoxin
May cause marked bradycardia, conduction problems or hypotension.
Common questions about latanoprost + timolol maleate
Answers are fully visible for fast scanning and source review.
Why combine two eye treatments?
They lower eye pressure through different mechanisms and are licensed when either treatment type alone is insufficient.
Can eye colour change permanently?
Yes. Brown iris pigmentation can increase gradually and may be permanent.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.