alverine citrate + simeticone at a glance
Medicine class
Musculotropic antispasmodic plus antiflatulent.
Licensed use
Relief of abdominal pain in adults with irritable bowel syndrome.
Administration
An oral soft capsule swallowed with water at the beginning of meals.
Allergy warning
Contains traces of soya lecithin and must not be used by people allergic to peanut or soya.
Driving
Dizziness or vertigo can occur; do not drive or use machinery if affected.
What is alverine citrate + simeticone used for?
The selected product is licensed for adults only.
Relief of abdominal pain in irritable bowel syndrome.
How does alverine citrate + simeticone work?
Alverine acts directly on intestinal smooth muscle to reduce spasm without an atropine-like action. Simeticone is not absorbed; it changes the surface tension of gas bubbles so they join together and disperse more easily.
How to take alverine citrate + simeticone
Take by mouth exactly as directed by the prescriber. Swallow the soft capsule with a glass of water at the beginning of a meal.
Do not use it if you have a peanut or soya allergy.
Do not take it if you have paralytic ileus, intestinal obstruction or severe constipation.
Seek medical review if symptoms are new, worsen or have not improved after two weeks.
alverine citrate + simeticone side effects
Common or expected effects
- Headache, dizziness or vertigo, nausea, rash, hives and itching have been reported; their frequency is not known.
Get urgent medical advice
- Severe allergic reaction, including facial or throat swelling, breathing or swallowing difficulty, or anaphylactic shock.
- Liver injury, which may cause jaundice, dark urine, pale stools, persistent nausea or vomiting, loss of appetite, tiredness or upper-right abdominal pain.
alverine citrate + simeticone in pregnancy
The selected combination product should be avoided during pregnancy as a precaution because evidence for simeticone and the combination is lacking. Anyone who is pregnant, planning pregnancy or exposed during pregnancy should discuss this with their prescriber rather than changing treatment without advice.
alverine citrate + simeticone while breastfeeding
The selected combination product should be avoided during breastfeeding because transfer of its ingredients or metabolites into milk is unknown. Specialist UK guidance says alverine alone can sometimes be used cautiously for a full-term, healthy infant, but alternatives are preferred; this does not override the combination product's specific restriction.
alverine citrate + simeticone interactions
No medicine interactions are currently known for the selected product, but interaction studies and clinical information may be limited. Tell your prescriber or pharmacist about prescription, non-prescription and complementary products.
No known medicine interactions
The product information identifies none, so no specific interaction-related adjustment is stated.
Common questions about alverine citrate + simeticone
Answers are fully visible for fast scanning and source review.
What is alverine citrate + simeticone used for?
It is licensed in adults to relieve abdominal pain associated with irritable bowel syndrome.
Can children take alverine citrate + simeticone?
The selected product is for adults only; safety and efficacy below 18 years have not been established.
Can alverine citrate + simeticone be taken during pregnancy?
The selected combination should be avoided during pregnancy because evidence for simeticone and the combination is insufficient. Discuss exposure or treatment needs with a prescriber.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.