Thrombotic Thrombocytopenic Purpura (TTP)
Emergency diagnosis and management of TTP.
Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Clinical Guidelines
A British Society for Haematology Guideline: Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies
National
British Society for Haematology Guideline: Diagnosis and management of thrombotic thrombocytopenic purpuraNational
British Society for Haematology Guideline: Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathiesNational
Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies (British Society for Haematology Guideline, 2023)National
NICE guideline [TA667]: Caplacizumab for treating acquired thrombotic thrombocytopenic purpuraNational
NICE guideline [TA667]: Recommendations for thrombotic thrombocytopenic purpuraNational
2025 focused update of the 2020 ISTH guidelines for management of thrombotic thrombocytopenic purpuraLocal
Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathiesLocal
Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) in Japan 2023Local
ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura (TTP)Local
ISTH guidelines for treatment of thrombotic thrombocytopenic purpuraLocal