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Medicines aprepitantQuestion & answer

aprepitant · Medicine question

Is taking St John's wort with EMEND (aprepitant) recommended?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Taking EMEND (aprepitant) with herbal preparations containing St John's wort (Hypericum perforatum) is not recommended.

Sources for this answer

EMEND 80mg, 125mg hard CapsulesMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 22Document updated 17 March 2021

Sources checked 8 November 2026

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aprepitant

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