Answer
Yes, riociguat is contraindicated in severe hepatic impairment classified as Child–Pugh C.
Sources for this answer
- Adempas 0.5 mg, 1.0 mg, 1.5 mg, 2.0 mg, 2.5 mg film-coated tabletsMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.3 Contraindications · Version 16Document updated
Sources checked