Answer
Kidney function is important because miglustat is mainly cleared in urine and exposure increases when renal function is reduced. Specialist assessment is required, and use in severe renal impairment is not recommended.
Sources for this answer
- Yargesa (miglustat) 100mg Hard Capsules — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.