Answer
Macitentan is active at both endothelin ETA and ETB receptors and is approximately 100-fold more selective for ETA than ETB receptors in vitro.
Sources for this answer
- Opsumit 10mg film coated tablets (Great Britain)Janssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §5.1 Pharmacodynamic properties · Version 29Document updated
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