Answer
Eltrombopag interacts with the transmembrane domain of the human thrombopoietin receptor (TPO-R), initiating signalling cascades similar but not identical to endogenous thrombopoietin and inducing proliferation and differentiation from bone marrow progenitor cells.
Sources for this answer
- Revolade film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 28Document updated
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